Moderator(s): Donna Lahey, RNFA, CNOR
84. Low density pedicle screw constructs are associated with lower incidence of proximal junctional failure in adult spinal deformity surgery
Wesley M. Durand1; Han Jo Kim, MD2; D. Kojo Hamilton, MD3; Renaud Lafage, MSc2; Peter G. Passias, MD4; Themistocles S. Protopsaltis, MD5; Virginie Lafage, PhD2; Justin S. Smith, MD, PhD6; Christopher I. Shaffrey, MD7; Munish C. Gupta, MD8; Eric O. Klineberg, MD9; Frank J. Schwab, MD2; Jeffrey L. Gum, MD10; Gregory M. Mundis Jr., MD11; Robert K. Eastlack, MD12; Khaled M. Kebaish, MD13; Alexandra Soroceanu, MD, MPH14; Richard A. Hostin Jr., MD15; Douglas C. Burton, MD16; Shay Bess, MD17; Christopher P. Ames, MD18; Robert A. Hart, MD19; Alan H. Daniels, MD20; International Spine Study Group21
1Brown University, Alpert Medical School, Providence, RI, US; 2Hospital for Special Surgery, New York, NY, US; 3University of Pittsburgh School of Medicine, Pittsburgh, PA, US; 4NY Spine Institute, NYU Langone Health, New York, NY, US; 5Department of Orthopaedic Surgery, NYU Langone Orthopaedic Hospital, NYU Langone Health, New York, NY, US; 6UVA Health System, Charlottesville, VA, US; 7Duke University, Durham, NC, US; 8Washington University School of Medicine, St. Louis, MO, US; 9 UC, Davis School of Medicine, Sacramento, CA, US; 10Norton Leatherman Spine Center, Louisville, KY, US; 11Scripps Clinic Medical Group, Department of Orthopedics, La Jolla, CA, US; 12Scripps Clinic, San Diego, CA, US; 13Johns Hopkins University, Baltimore, MD, US; 14University of Calgary, Calgary, Canada; 15Southwest Scoliosis Institute, Dallas, TX, US; 16University of Kansas Medical Center, Kansas City, KS, US; 17Denver, CO, US; 18University of California, San Francisco, San Francisco, CA, US; 19Swedish Neuroscience Institute, Seattle, WA, US; 20Warren Alpert Medical School of BU/RI Hospital, Providence, RI, US; 21Brighton, CO, US
FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs.
85. Incidence and resolution strategies for early onset postoperative leg pain following lumbar total disc replacement
Richard D. Guyer, MD1; Scott L. Blumenthal, MD1; Donna D. Ohnmeiss, PhD1,2; Nicole Ferko, MSc3; Ashley Bonner, PhD4; Aaron Situ, MSc, BS4
1Center for Disc Replacement at Texas Back Institute, Plano, TX, US; 2Texas Back Institute Research Foundation, Plano, TX, US; 3Cornerstone Research Group, Burlington, ON, Canada; 4Eversana, Burlington, ON, Canada
FDA Device/Drug Status: activL and ProDisc-L (Approved for this indication)
86. Why are DBMs so variable? Influence of fibers, carrier, and tissue bank
Gregory M. Mundis Jr., MD1; Nick Russell, PhD2; William. Walsh, PhD3; Peter Kim, MS4; Jennifer Chen, PhD5; Frank Vizesi, PhD, PhD5
1Scripps Clinic Medical Group, Department of Orthopedics, La Jolla, CA, US; 2Carlsbad, CA, US; 3Surgical and Orthopaedic Research Labs, Randwick, Maroubra, Australia; 4SeaSpine Orthopedics, Carlsbad, CA, US; 5SeaSpine, Carlsbad, CA, US
FDA Device/Drug Status: Grafton (Approved for this indication), DBX Putty (Approved for this indication), Optium Putty (Approved for this indication)
87. Rates of loosening, failure, and revision of iliac fixation in adult deformity surgery
Robert K. Eastlack, MD1; Alexandra Soroceanu, MD, MPH2; Gregory M. Mundis Jr., MD3; Alan H. Daniels, MD4; Justin S. Smith, MD, PhD5; Breton Line, BS6; Peter G. Passias, MD7; Pierce D. Nunley, MD8; David O. Okonkwo, MD9; Khoi D. Than, MD10; Juan S. Uribe, MD11; Dean Chou, MD12; Khaled M. Kebaish, MD13; Christopher I. Shaffrey, MD14; Shay Bess, MD15; International Spine Study Group16
1Scripps Clinic, San Diego, CA, US; 2University of Calgary, Calgary, Canada; 3Scripps Clinic Medical Group, Department of Orthopedics, La Jolla, CA, US; 4Warren Alpert Medical School of BU/RI Hospital, Providence, RI, US; 5UVA Health System, Charlottesville, VA, US; 6Denver International Spine Center, Denver, CO, US; 7NY Spine Institute, NYU Langone Health, New York, NY, US; 8Spine Institute of Louisiana, Shreveport, LA, US; 9Pittsburgh, PA, US; 10Duke University, Durham., NC, US; 11Barrow Neurological Institute, Phoenix, AZ, US; 12University of California San Francisco, San Francisco, CA, US; 13Johns Hopkins University, Baltimore, MD, US; 14Duke University, Durham., NC, US; 15Denver, CO, US; 16Brighton, CO, US
FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs.
88. Cell stiffness decreases with severity of disc degeneration and inflammatory stimulation
Nadeen Chahine, PhD1; Eric Leung, BA2; Meghan Cerpa, MPH3; Meghana Vulapalli, BS4; Venkat Boddapati, MD1; Timothy Jacobsen, MEng1; Ronald A. Lehman Jr., MD5
1New York, NY, US; 2The Spine Hospital, New York, NY, US; 3Columbia University Medical Center, New York, NY, US; 4Columbia University Medical Center, New York, NY, US; 5The Spine Hospital -Columbia University / New York Presbyterian, New York, NY, US
FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs.
89. Is academic department teaching status associated with adverse outcomes after lumbar fusion for degenerative spine diseases?
Dean C. Perfetti, MD, MPH 1; Daniel Kiridly, MD, MBA2; Matthew Morris, MD3; Alan Job, MD4; Austen Katz, MD5; Jeff S. Silber, MD, DC6; David A. Essig, MD7
1Department of Orthopedic Surgery, Long Island Jewish Medical Center, New Hyde Park, NY, US; 2Northwell Health Orthopaedic Surgery, New Hyde Park, NY, US; 3Bronx, NY, US; 4Northwell Health North Shore-LIJ, New Hyde Park, NY, US; 5Long Island Jewish Hospital, Queens, NY, US; 6Great Neck, NY, US; 7Northwell Health, Great Neck, NY, US
FDA Device/Drug Status: This abstract does not discuss or include any applicable devices or drugs.
90. Nanoroughened microstructured orthopaedic implant surfaces induce osteogenesis via soluble signaling factors produced by MSCs
Michael Berger, BS1; David Joshua Cohen, MD2; Kyla Bosh2; Michelle B. Gallagher, MS3; Paul J. Slosar, MD4; Zvi S. Schwartz; Barbara D. Boyan, PhD5
1VCU College of Engineering, Department of Biomedical Engineering, Richmond, VA, US; 2Virginia Commonwealth University, Richmond, VA, US; 3Medtronic (Titan Spine), Mequon, WI, US; 4SpineCare Medical Group, Daly City, CA, US; 5Richmond, VA, US
FDA Device/Drug Status: Interbody Fusion Implants (Approved for this indication)
Discussion